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食物钙含量与骨密度骨折关系PURE

日期:2020-04-08 15:04:11浏览次数:

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The association of calcium intake with osteoporotic vertebral
fractures in a large Chinese cohort
The effect of calcium on prevention of osteoporosis and related fracture which are aging issues is unclear. The
aim of this study is to explore the association of calcium intake with vertebral fracture. This study enrolled
3,457 participants from China Action on Spine and Hip Status (CASH) study from 2013 and 2017. Dietary calcium
intake was collected using validated food frequency questionnaires (FFQ). Vertebral fracture of CT images was
defined as the primary outcome. The mean calcium intake of men and women were 522.75mg/day and
507.21mg/day, respectively. 6% reduction in the odds of fracture risk was observed per 100 unit increase of
calcium intake from food among females (OR, 0.94; 95% CI, 0.89-0.99), but results among males were not
significant. We divided calcium intake into quintiles when modelling its associations with fracture risk, negative
associations of fracture risk with calcium intake were found among females. In a population with low usual
calcium intake, higher dietary calcium intake was associated with fewer vertebral fracture in women and that
no such association was seen in men.

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